Medication that might trigger heartburn

Medications That Directly Irritate the Esophagus and reduce the protective lining of the stomach and can also affect the esophagus:
- Examples: Alendronate, risedronate, Potassium Supplements (Especially potassium chloride tablets), Iron Supplements, NSAIDs, corticosteroids, some Antibiotics: (e.g., tetracycline), Chemotherapy
Medications That Relax the Lower Esophageal Sphincter (LES):
- Examples: Anticholinergics: (e.g., atropine, some bladder medications), Calcium Channel Blockers: (e.g., nifedipine, amlodipine), Theophylline, Nitrates (e.g., nitroglycerin), Some Hormones: Progesterone and OCPs, Alpha-blockers: (e.g., prazosin, terazosin), Barbiturates and Benzodiazepines (BZDs), Dopamine Tricyclic Antidepressants (TCAs)
Medication that reduce gastric motility
- Examples: Narcotic Analgesics (Opioids), Beta-blockers: (e.g., propranolol, atenolol), Barbiturates and Benzodiazepines (BZDs), Tricyclic Antidepressants (TCAs)

NEPHA